Thursday, May 20, 2021

Dissolution, Bioavailability & Bioequivalence

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1. Evolution of dissolution screening 5; 2. Theory of dissolution 11; 3. Theoretical principles for the release of a drug from dose types 37; 4. Result of the physicochemical homes of the drug on dissolution rate 53; 5. Aspects impacting the rate of dissolution of solid dosage kinds 73; 6. Results of storage and product packaging on the dissolution of drug formulas 107; 7. Factors relating to the dissolution device 115; 8. Result of the test criteria on dissolution rate 145; 9. Dissolution of suspensions 173;10 Dissolution of topical dosage forms (creams, gels, and ointments) 189;11 Dissolutions of suppositories 205;12 Dissolution qualities of controlled-release systems 215;13 Techniques for improvement of the drug-dissolution qualities 265;14 Establishing a new dissolution technique 285;15 Bioavailability, meanings and historic viewpoint 297;17 In vitro modeling for drug absorption 315;18 Pharmacokinetic factors to consider in bioavailability studies 335;19 Bioavailability and variations in drug blood levels 367;20 Bioavailability and the biologic response 385;21 Measurements of bioavailability 399;22 General issues to be thought about in conducting bioavailability studies 415;23 Bioavailability of controlled-release dosage forms 425;24 In vivo release and bioavailability of topical preparations 437;25 Approaches for improvement of bioavailability 455;26 Bioequivalence: basic meanings 477;27 Bioequivalence: medical history 481;28 Correlation of in vitro rate of dissolution with in vivo bioavailability 491;29 Determination of bioequivalence and its regulatory elements 517;30 The official bioequivalence protocols and restorative equivalence 533.

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